Our Science


Kharisence is the obtained by a proprietary stage sono-fermentation process. Inspired by traditional Japanese food, Natto,  the first stage of sono-fermentation is similar to Natto** fermentation process. The second stage of sono-fermentation process is to infuse the Swiss Rose stem cells*** to the fermentation broth. It is the birth of the ultimate Elixir, Kharisence. It is full of vitamins, amino acids, minerals, peptides, enzymes and polysaccharides that work together to make your skin healthier and younger looking.  Even the driest complexions are healed in the ultimate ritual of renewal.

** Natto is a 1,000-year-old Japanese dietary staple made from soybeans that have been soaked and fermented. Japanese discovered that Natto make people healthier, more energetic, lived longer and skin looks better. Recently research showed it can dramatically increase the collagen production in human skin fibroblasts and hyaluronic acid production in human skin cells.

*** Stem Cell shave a unique ability to replace damaged and diseased cells. As they divide, they can proliferate for long periods into millions of new skin cells.​ As we age, our stem cells lose their potency. Your skin's ability to repair itself just isn't what it used to be. The result can be fine lines, wrinkles, age spots, and sagging skin. The Alpine rose grows at very high altitudes. Its leaves have adapted to cold, dryness and high level UV, so that it can resist these harsh environmental assaults and fast changes. The stems cells contain special epigenetic factors and metabolites that are able to preserve and potentially activate the human skin stems’ function.


Living Water

Water is the cluster of H2O molecules with different sizes, smaller clusters have higher energy. Our living water clusters have the following benefits:

  • Smaller cluster water penetrate skin much faster, Higher hydration power

  • Smaller cluster water is much more effective as carrier to bring actives to skin for better efficacies

  • Anti-oxidation power



Not All Resveratrol Are the Same. There are two forms of resveratrol: cis-resveratrol and trans-resveratrol. Many studies shows it is trans-resveratrol not cis-resveratrol provides all the benefits of resveratrol. Cis-resveratrol is not stable, while trans-resveratrol is stable for months. Symbélle has double amount of trans-resveratrol to the leading brands.



Free radicals are harmful molecules that can be anywhere, including in the air you breathe, cigarette smoke or the foods you eat. Antioxidants protect the body’s cells from damage due to free radicals.

You’ve heard it a million times: The best way to stay healthy is to eat a wide variety of vitamin-rich and antioxidants foods. But eating a wide variety of foods can sometimes be difficult in our on-the-go culture.


Hydrolyzed Collagen

Collagen peptides are used as a bioactive ingredient in nutricosmetic products and have been shown in preclinical studies to improve skin barrier function, to induce the synthesis of collagen and hyaluronic acid, and to promote fibroblast growth and migration.